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An adverse response to antimalarial medication - and a fatal reaction to fava beans

Objectives

By the end of this exercise you should be able to:

Describe the pentose phosphate pathways and explain its importance as a source of NADPH and pentose sugars

Explain the role of glutathione in protection against oxidative damage and how impaired activity of glucose 6-phosphate dehydrogenase leads to haemolysis

Explain why only males are normally affected by an X-linked recessive genetic disease

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