Metabolism
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How is NADH from glycolysis normally re-oxidised?
Objectives
By the end of this exercise you should be able to:
Describe the malate-aspartate shuttle for transfer of reducing equivalents from the cytosol into mitochondria
Describe the glycerol phosphate shuttle for transfer of reducing equivalents from the cytosol into mitochondria
Explain why the glycerol phosphate shuttle is less energetically efficient than the malate-aspartate shuttle, but is important in tissues with a high rate of glycolysis